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Description

GLP-1 RAs provide sustained central and peripheral GLP-1R activation that blunts appetite via hypothalamusvagusNTS circuits, improves metabolic health, and may reduce alcohol and other substance-related craving and reward signals.

Oxid Med Cell Longev

Conversely, VLEKT, which induces nutritional ketosis, may be more appropriate for patients with significant cardiometabolic comorbidities, offering rapid and substantial fat mass reduction and improved glycaemic control

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This issue of the HPCs DataPoints series explores trends in GLP-1 prescriptions in Massachusetts through September 2023 and examines the use and spending impacts of these drugs in the Commonwealth.