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These realities highlight why Ozempic works best as part of a long-term, structured approach rather than a short-term solution

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While heavier individuals may have slightly lower plasma concentrations at a given dose, the medication's efficacy has been demonstrated across a wide range of body weights in clinical trials

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In overweight humans, liraglutide 3 mg solidly inhibits gastric emptying after 5wk of treatment, but the efficacy markedly decreases after 16wk of treatment, yet with still significant effect relative to placebo treated controls [808]

Buse JB, Sesti G, Schmidt WE, et al