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JAMAs Post JAMA 219,574 followers Report this post Use of GLP-1 agonists for weight loss, compared with use of bupropion-naltrexone, was associated with an increased risk of pancreatitis, gastroparesis, and bowel obstruction but not biliary disease

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Overall, GLP-1 and GLP-1RAs (as shown in Figure 2) can improve lung function, and airway remodeling, reduce mucus secretion, reduce disease risk and mortality through a variety of pathways, and may hold potential promise in the treatment of airway disease, 80 but GLP-1RAs are not approved for the treatment of COPD, so further studies are needed to confirm this