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DPP-4 inhibitors can also be combined with an insulin therapy

Combined SGLT2i and GLP-1RA therapy resulted in a significantly lower risk of all-cause death, non-fatal myocardial infarction, and non-fatal stroke at 12 months than SGLT2i monotherapy (HR, 1.77

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Higher doses are more likely to cause these symptoms, which is why starting low and going slow is so important

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH