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Do not stop or change your GLP-1 dose on your own based on online posts, since most side effects ease over several weeks as the body adjusts

As mentioned earlier, a key limitation of incretin therapy in diabetes is the short half-life of native GLP-1, which necessitates frequent administration

Wegovy is also a semaglutide drug and is the same medication as Ozempic, just at a higher dosage

While the profile of exendin-4-mediated signalling is more similar to that of GLP-1, there are differences in receptor engagement by the two peptides that can be rationalised by the structural and dynamic data

While semaglutide commonly causes mild gastrointestinal symptoms like nausea during dose escalation, severe or persistent right-sided abdominal pain differs from typical GI side effects and may indicate hepatobiliary issues