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The primary analysis evaluated the ratios of area under the plasma concentrationtime curves (AUCs) and maximum plasma drug concentration (Cmax) of renal impairment versus the normal renal function group (90% confidence interval [CI])

Across all drinkers, average weekly alcohol intake dropped from 11.3 to 4.3 units

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New GLP-1 pill helps patients lose up to 8% of body weight, trial shows Orforglipron led to greater weight loss than semaglutide tablets and could offer more effective oral alternative to jabs A new daily pill could be a more effective GLP-1 tablet for weight loss, according to a clinical trial that may pave the way for an improved non-injection alternative to Wegovy and Mounjaro