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When to seek urgent medical advice : Sudden worsening of joint pain, swelling, or stiffness Signs of infection (fever, malaise, localised warmth) Severe abdominal pain (potential pancreatitis if on GLP-1 therapy) Unexplained persistent nausea or vomiting Any concerning new symptoms after starting any new medication According to NICE Quality Standard 33, if you have suspected persistent synovitis, you should be referred to rheumatology within 3 working days and assessed within 3 weeks
Given the high mortality rates for patients on VA-ECMO (hospital mortality is approximately 50%, and 6-month survival is as low as 30%), patient selection is key

And again, a lot of our listeners are moms

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Because metformin can be COMBINED with other medications to produce even BETTER results

Both are valid options
