glp-1 cancer Agents vs Aspirin: A New Era in Colorectal Prevention GLP-1s appear to cut cancer
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Proven Efficacy: Clinical trials have shown that high-dose oral semaglutide produces weight loss results comparable to the injectable versions
Similarly, while no dose adjustment is required, caution should be exercised in patients with severe hepatic impairment due to limited clinical experience

doi:10.1016/j.cmet.2012.05.012 43

Most people begin at 0.25 mg weekly, escalating to 0.5 mg in Week 5, then moving toward 1.0 mg and potentially higher maintenance doses
Ryan DH