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99 Another 8-week aerobic exercise intervention demonstrated an 11.92% and 45.45% increase in serum total osteocalcin and undercarboxylated osteocalcin levels, respectively, in the exercise group, and no dramatic changes were observed in the control group
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The SCFAs not metabolized in colonocytes enter the portal circulation of the liver through the basolateral membrane and provide substrates for energy metabolism in hepatocytes

Ali S., Ahmad K., Shaikh S., et al., Identification and Evaluation of Traditional Chinese Medicine Natural Compounds as Potential Myostatin Inhibitors: An in Silico Approach, Molecules 27, no

Comparative metabolic and hepatic effects of GLP-1-based mono-, dual-, and triple-agonist therapies GLP-1 receptor signaling Intestinal L-cells serve as the primary source of GLP-1 synthesis, which operates via G-protein coupled receptors present in pancreatic beta cells, gastrointestinal and central neural systems, cardiac tissues, and kidneys [26]
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