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When GLP-1 receptors are activated, this signal gets dampened

PMID: 145 WuS.LuQ.DingY.WuY.QiuY.WangP.et al

GLP-1 is a 30-amino acid peptide hormone produced by differential post-translational processing of the proglucagon precursor protein by prohormone convertase 1/3 (PCSK1) in intestinal L-cells and in neurons of the nucleus tractus solitarii (NTS) in the brainstem
Liraglutide has a short half-life of about 13 hours, meaning you must inject it every single day

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