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Lancet 2023, 402, 705719
This is a good time to reassess your eating habits and ensure youre getting adequate nutrition despite reduced appetite
Generally, healthcare professionals recommend increased exercise and a lower-calorie diet, but prescription medications may be recommended if sufficient weight loss is not achieved after six months

Diabetes 3 , 16 (2012)

In the head-to-head SURMOUNT-5 trial (NEJM 2025), tirzepatide produced 20.2% weight loss vs 13.7% for semaglutide
This leaves you lighter but not leaner, a condition sometimes called being skinny fat
