not losing weight on tirzepatide compound Tirzepatide? Dietitian Explains Why Compounded Tirzepatide - Medical Weight

For someone who weighs 200 lbs., this is a weight loss of just 10-15 lbs

NICE recommends periodic review of weight, glycaemic control (in diabetic patients), and overall wellbeing

Contact of nutrients with L-cells in the distal gut likely explains the prolonged duration of elevated GLP-1 during meals, and it might also be responsible for the typically observed increased levels of GLP-1 following gastric bypass and, albeit less so, after sleeve gastrectomy surgery [[211], [212], [213], [214], [215], [216]], because surgical repositioning of the distal gut more rapidly exposes the distal L-cells to incoming nutrients [144]

Start Ozempic, Wegovy, or Mounjaro, and you will see fast changes in appetite and weight

was 41.9%

But the GLP-1 receptor is expressed far beyond the gut and pancreas