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Regarding gastric emptying, injectable GLP-1RA generally produces a more pronounced and sustained delay, whereas oral semaglutide shows a modest, early-phase effect that attenuates at steady state [74]

7 For patients with type 2 diabetes who have atherosclerotic cardiovascular disease or are at high risk for it or who have kidney disease or heart failure, either a GLP-1 receptor agonist or an SGLT-2 inhibitor with demonstrated cardiovascular benefit with or without metformin is recommended, independent of the hemoglobin A1c level (level of evidence A)

[PubMed] 55.Smits M.M., Van Raalte D.H

The treatment process includes a comprehensive initial consultation, followed by a customized plan that incorporates either Semaglutide or Tirzepatide

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These are real changes in brain chemistry