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The findings suggest semaglutide could become an important tool for clinicians treating both CKD and type 2 diabetes, according to Matthew Weir, MD, professor and chief of the division of nephrology at University of Maryland School of Medicine

Onitilo, A

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While peripherally administered GLP-1 seemingly crosses the blood brain barrier (BBB) via simple diffusion, the half-life of GLP-1 is less than 2 min, leading to disagreement regarding whether peripherally derived GLP-1 is what activates CNS GLP-1R under physiological conditions

Anaesth Rep 2024;12:e12278.ArticlePubMedPMC 18