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Notably, proteins such as MRPS36 and RNF181 were significantly upregulated, while ABCB9 and RIC1 were downregulated

Furthermore, in rodents like mice and rats, stimulating the GLP-1 receptor raises cAMP in thyroid C cells, initiates the release of calcitonin, and upon longer-term exposure, is accompanied by C-cell proliferation and the formation of C-cell adenomas and (medullary thyroid) carcinomas (6)

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doi: 10.1186/S13098-022-00785-1

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Therefore, it was concluded that clinically significant pharmacokinetic changes are unlikely to occur