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Background: The evidence on berberine stimulating the secretion of GLP-1 in intestinal L cell has been studied

But what if there was a sugar

However, genetic variants can alter the response in some.

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Incretin based therapies with glucagon-like peptide-1 receptor agonists (GLP-1RA) are already established in the treatment of type 2 diabetes

Here, the authors review the physiological roles of GLP-1, the potential renoprotective mechanisms of incretin-based therapies and the available renal outcome data from clinical trials.
