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Will stopping GLP-1s cause blood sugar problems

By keeping food in your stomach longer, semaglutide extends the sensation of fullness and reduces overall calorie intake, which drives weight loss

According to the pharmaceutical firm Eli Lilly, a 40-week phase 3 clinical trial of orforglipron in people with diabetes found the medication reduced blood sugar levels and helped patients shed pounds

Adherence in real-world settings is often limited by side effects, cost, and perceived lack of benefit, complicating translation from trials to clinical practice (Table 2)

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Tirzepatide, with its dual pathway, showed greater average reductions than semaglutide over the study period in trials