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Researchers from the German Center for Diabetes Research (DZD) and Helmholtz Munich, in collaboration with a colleague from the University of Santiago de Compostela in Spain, describe the development of incretin-based pharmacotherapy from its beginnings to the discovery of polyagonists

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A growing body of work suggests GLP-1 drugs act on platelets, immune cells, and vascular cells to protect against atherosclerosis independently of their effects on glycemia, appetite, and weight

Semaglutide had the highest market share of oral GLP-1 agonists in 2025 by contributing nearly 52.8% of the sales with high clinical efficacy, primary use and oral formulations made available