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So far, the co-agonist drugs which have reached phase 2 trials have demonstrated an improved glycaemic profile with chronic administration

The medication may interfere with the psychological control that binge eating has on the person by reducing the motivations of hunger and reward

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While this is not as much weight loss as seen with other agents, metformin is well tolerated and safe, and it helps treat insulin resistancean additional benefit, given that many of our patients are diabetic or prediabetic

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Research progress of glucagon-like peptide-1 (GLP-1) analogues [J]