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Glucagonlike peptide1, but not glucosedependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

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A study using in situ hybridization and polymerase chain reaction techniques did not detect GIP expression in the brain of adult male Sprague-Dawley rats (41)

Treatment discontinuation due to side effects occurred in 4.3%, 7.1%, 6.2%, and 2.6% of participants in the 5, 10, 15 mg, and placebo groups, respectively [18]