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Description
As noted under baseline characteristics, patients included in PIONEER 9 and 10 weighed less at baseline compared to patients in PIONEER 1 to 6 and 8

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Kidney injury Cases of renal impairment with dehydration have occurred, causing severe GI symptoms

Its safe for long-term use when followed as directed

[DOI] [PubMed] [Google Scholar] 71.Wyszomirski K., Waldziak M., Raska-Waldziak A

We need these therapies to work for decades in humans
