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179,180 In theory, enhancing mitochondrial efficiency while reducing oxidative burden could promote muscle anabolism by redirecting nutrient partitioning toward muscle protein synthesis, thereby countering sarcopenia and functional decline

A novel oral formulation of the GLP-1 receptor agonist semaglutide (Rybelsus) was recently approved for the treatment of T2DM

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While trevogrumab binds to and inhibits myostatin, a protein that limits skeletal muscle growth, garetosmab neutralizes a protein called activin A, which is linked to muscle atrophy

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