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Therefore, GLP-1 should not induce hypoglycemia when administered alone or with other antidiabetic agents that do not cause hypoglycemia, such as metformin (MET), thiazolidinediones (TZDs) and alpha-glucosidase inhibitors (AGIs)

Glucose-dependent insulinotropic peptide signaling pathways in endothelial cells

Diabetes Obes Metab 15: 713720, 2013

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Current disease-modifying treatments on the market focus on suppressing the immune attack to the central nervous system
