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Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like Peptide-1 loss of function

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Total daily berberine of 1000 to 1800mg is consistent with clinical trial dosing

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Further, our findings may not be generalisable to youth with severe hyperglycaemia or those on chronic treatment and, due to limitations in sample size, we were only able to explore potential mediators of metformin response

[DOI] [PubMed] [Google Scholar] 77.Liarakos A.L., Tentolouris A., Kokkinos A., Eleftheriadou I., Tentolouris N