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Regulatory authorities continue to review emerging safety data as longer-term studies become available, ensuring that prescribing guidance reflects the most current evidence base

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Importantly, these effects are shared across species from rodents to humans, as peripheral GLP1 administration to normal and diabetic human subjects induced satiety and reduced food intake in short term studies (Flint et al., 1998

In a Phase 2 trial published in The New England Journal of Medicine , patients lost up to 24.2% of their body weight in just 48 weeksnearly a quarter of their total weight