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Description
In the SURMOUNT-1 trial, tirzepatide at 15 mg weekly resulted in up to 22.5% body weight reduction over 72 weeks (Jastreboff et al., 2022)
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The GIP component of tirzepatide further decreases food intake and increases energy expenditure, resulting in weight reduction somewhat better than the GLP-1 alone
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Yes, significant weight loss can lead to feeling cold as the body adjusts to having less insulation and possibly lower energy levels
Non-Exercise Activity Thermogenesis (NEAT): This is the energy spent on everything we do that isn't sleeping, eating, or sports-like exercise
