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Single-agent or evidence-based dual protocols remain the safer starting point

The studies evaluating the efficacy of combined low-dose liraglutide with metformin vs

10.1073/pnas.84.10.3434 34 DuX.JinJ.ShangQ.KongX.TangL.LiuW

At week 72, 37.0% of people treated with semaglutide 2.4 mg achieved improvement in liver fibrosis with no worsening of steatohepatitis compared to 22.5% on placebo