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So when someone says, GLP-1s cause muscle loss, the first question should be: what exactly was measured

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Performance (Compared to GLP-1 Only)Less lethargy reported by some usersGlucagon activity may support energy levels

Exposures New users of GLP-1RA were separately compared with new users of dipeptidyl peptidase-4 inhibitors (DPP4i) and sodium-glucose cotransporter 2 inhibitors (SGLT2i), using 1:1 propensity score matching to adjust for differences in patient characteristics