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DOI 10.1007/s00210-014-1056-3 Beakley BD et al (2015): Tramadol, pharmacology, side effects, and serotonin syndrome: a review

It's a chronic treatment for as long as it's beneficial and safe: the doctor reviews your response every 3 months and decides with you whether to continue, adjust or stop

This unique mechanism helps regulate blood sugar while producing stronger appetite suppression in many individuals

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Counterintuitively, drinking more water helps reduce water retention because it signals to your body that fluid is plentiful and there is no need to hold onto it

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