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GLP-1 medications including semaglutide can trigger gout flares in some patients due to rapid weight loss and uric acid elevation

During GGIT, semaglutide significantly increased ISR to levels similar to those in healthy participants

Upcoming Removal of Selected GLP-1 Drugs from Medi-Cal Rx Effective January 1, 2026, Californias Medi-Cal Rx program will remove certain medications from its contract drug list

Reduce the risk of heart failure exacerbations by 40% and hospitalizations by 33%

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