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Description
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2015 Feb;26(2):589-99

Tirzepatide combines GLP-1 and GIP receptor activation, potentially offering faster results

Higher GLP-1 RA doses and, especially, the duration of treatment influenced the risk [61]

Published Phase 2 data (NEJM, 2023) showed retatrutide achieving up to 24.2% mean weight reduction at 48 weeks exceeding outcomes seen with dual GLP-1/GIP agonists

This smoother glucose curve reduces the likelihood of reactive hunger and subsequent overeating