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Importantly, activation of GLP-1Rs in the CNS shows similar anti-lipemic actions as peripheral administration, where ICV injection of exendin-4 markedly suppressed chylomicron excursion [66]

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Recovery is often gradual and uneven, but improvement is common

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Moreover, GLP-1RAs can alleviate vascular remodeling expressed as neointimal hyperplasia after induced vascular injury

Utsugisawa, K
