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The Phase 3 ATTAIN-1 trial had good results that led to this approval, but not all positive: 12.4% average weight loss (27.3 lbs) at highest dose Lower than the 15-20% weight loss seen with injectables Wegovy and Zepbound Nearly 1/4 of participants on the highest dose reported vomiting Vomiting rates are much higher than injectable GLP-1s However, there is likely a niche for Foundayo (along with the pill version of Wegovy) due to convenience: No refrigeration requirements or injection site reactions Eliminates barriers for patients avoiding injectables due to stigma, needle aversion, or storage constraints It's possible we could see this as a "maintenance" therapy after an initial injectable course

This Collection calls for papers that investigate the expanding clinical and biological roles of GLP1 RAs

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If needed, the pen can be kept at room temperature up to 30C for a total of 21 days

Explore the evidence on semaglutide safety, established colorectal cancer risk factors, and when to speak to your GP about concerns with this diabetes medication.