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Ramos-Lopez et al

These data come from Cosmos, a dataset created in collaboration with a community of Epic health systems representing more than 300 million patient records from 1,800 hospitals and more than 41,000 clinics from all 50 U.S

A previous study found that the highest dose of tirzepatide leads to an average loss of 15 percent of body weight over 72 weeks
Mechanism of gastrointestinal effects: Semaglutide mimics the naturally occurring hormone GLP-1, which is released from the intestine after eating

October 2023 : A study of 16 million patients (2006-2020) found that those who used GLP-1 agonists for weight loss were at a higher risk of pancreatitis, bowel obstruction, and gastroparesis compared to those who took bupropion-naltrexone instead
JGH Open 2018
