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Description
Commonly reported side effects may include nausea, decreased appetite, mild fatigue, or digestive changes

These drugs help improve blood sugar and can lead to weight loss, explains Kunal Shah, MD, an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center

Transitioning from one medication to another could cause temporary discomfort or unexpected reactions

Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes

While there is no absolute contraindication, alcohol can: Increase nausea and gastrointestinal distress Contribute empty calories that undermine weight management efforts Potentially increase the risk of hypoglycemia in patients also taking diabetes medications Impair judgment regarding portion control and food choices Potentially increase pancreatitis risk, especially with heavy consumption Patients should discuss alcohol use with their healthcare provider and, if consuming alcohol, do so in moderation (defined as up to one drink per day for women and up to two drinks per day for men)

For a full three-way comparison including semaglutide, see our complete GLP-1 comparison
