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One patient developed bilateral papillitis, which involves swollen optic nerves that can cause impaired vision, and another had paracentral acute middle maculopathy, which leads to a blind spot in the retina
She also suggests speaking to a behavioral health provider beforehand to screen for issues that could exacerbate mental health problems while on the medication, such as eating disorders or unmanaged mental health concerns
Currently, there are 3 GLP-1 agonists that are FDA-approved for the treatment of obesity: Saxenda (Liraglutide)- a once-daily subcutaneous injection given in the back of the arm, the thigh, or the abdomen
The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, with contraindications for patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
That raises familiar FDA considerations
Hypothalamic GPCR signaling pathways in cardiometabolic control
