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A recently published, randomized, placebo-controlled trial found a greater reduction in BMI z-score (0.22 SDs) in adolescents receiving liraglutide compared with placebo

Patients with no history of uveitis have a far reduced risk of developing the eye inflammation when taking GLP-1 drugs to treat diabetes or obesity.

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It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.