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Significance of the Topic The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists, particularly semaglutide, has transformed treatment strategies

Semaglutide was approved in 2017 as Ozempic for diabetes, and in 2021 as Wegovy for obesity

Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can reduce CV risk in patients with T2D, and both are recommended by the American Diabetes Association to reduce the risk of major cardiovascular events (MACE)

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Smriti Choudhary, MD, at Primary Care Center of Clear Lake.

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