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Those who have successfully implemented sustainable changesincluding regular physical activity (UK Chief Medical Officers recommend at least 150 minutes of moderate-intensity activity weekly), improved dietary patterns, and behavioural strategies for weight managementmay have better outcomes if discontinuing GLP-1 therapy

That is a clinically significant reduction, comparable to what you would expect from a dedicated blood pressure medication

There is no argument that the drugs are much more potent and faster acting than your bodies natural GLP-1 hormones

Studies show: Lowering inflammation with GLP-1s can slow the rate of joint damage in RA If you have RA and obesity or diabetes, takingGLP-1 meds can mean fewer flares and less need for extra medicine

Clinical studies suggest that GLP-1 analogs can mitigate symptoms in patients with Crohns Disease and Ulcerative Colitis by reducing macrophage activation and restoring epithelial integrity (Cani et al., 2016)