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In general, this service is intended to accelerate weight loss when used as part of a healthy lifestyle including diet and exercise

The catch is that your appetite-regulating hormones (leptin, ghrelin, PYY) remain dysregulated for 12-24 months, making weight regain likely through increased hunger and reduced satiety

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For tirzepatide, the gastric emptying effect is most pronounced after the first dose and tends to diminish with continued treatment, a phenomenon known as tachyphylaxis

Taheri, S., Lin, L., Austin, D., Young, T., & Mignot, E

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