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Incidence of hypoglycaemia with tirzepatide was similar vs placebo and lower vs basal insulin

A meta-analysis of randomized-controlled trials

Moran G, ONeill C, Padfield P, McLaughlin J

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So while theres no venom in your prescription vial, there is a legacy inside itone that started in the desert with a thick-skinned lizard that most people had written off as a slow, strange relic

This mechanistic framework may help explain why semaglutide shows robust efficacy for glycemic control and weight loss, but also why some adverse effects and tissue-adaptive responses emerge with continued administration (Figure 1)