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This compound presented a 350-fold reduction in potency at human GLP-1R, using the cAMP accumulation assay, to 30 nM as compared to 87 pM for the non-glycosylated Ab#2_GLP1 fusion

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, Lehtonen, J

February 2, 2026: Gastroparesis is Most Common Injury in Lawsuits Against Ozempic and Other GLP-1 Drugs According to court documents, gastroparesis is the most frequently listed injury in complaints filed as part of the GLP-1 product liability litigation (MDL -3094), which includes Ozempic claims