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doi: 10.1073/pnas.84.10.3434 10 KreymannBWilliamsGGhateiMABloomSR

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Similarly, if injection site reactions become progressively worse rather than improving, show signs of infection (increasing warmth, spreading redness, pus, or red streaking), or fail to resolve within several days, medical assessment is warranted

At that point, she called off work and mostly stayed in bed feeling sick

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