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The exact mechanism is not fully understood, but gastrointestinal effects and possible changes to saliva composition may contribute to metallic, bitter, or unpleasant taste sensations

10.1016/j.yhbeh.2020.104778 77 WalleniusV.EliasE.ElebringE.HaismaB.CasselbrantA.LarraufieP.et al (2020)

Semaglutide has the advantage of being well-established in this area, while Retatrutide is still in clinical trials

Worse, they think you can take the drug for only a short while and keep the weight off permanently afterwards, but all the research shows that this isnt true: people put the weight back on after stopping the drug. The side effects of the popular weight loss drugs, which can include sickness and diarrhoea, have resulted in people stopping taking them

The clinical benefits of Wegovy for weight managementwith average weight loss of 1215% of body weight in clinical trialsshould be weighed against potential adverse effects on an individual basis

Market analysts project peak annual sales for Mounjaro to range between $15 billion and $25 billion
