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The following serological markers will be assessed: fasting insulin, C-peptide, fasting glucagon, fasting plasma glucose, 2-h postprandial glucose, glycated albumin, leptin, adiponectin, lipid profile (triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol), liver function, renal function, gastrin-17, motilin, 5-HT, DA, HbA1c, and cholecystokinin

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(4) Reduced caloric intakeall combined effects result in 2035% spontaneous caloric reduction without deliberate dietary restriction

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