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GLP-1 activity also helps the pancreas release insulin when blood sugar is high

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Continuous therapy avoids the need to restart entirely and maintains steady progress without the rebound cycle

A subset of these reports involved patients with renal impairment, some of whom were prescribed inappropriate doses of sitagliptin
A plateau does not always mean the medication has stopped working. It may mean the treatment plan needs to be reviewed as a whole

doi: 10.2337/dc13-0234
