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The SURMOUNT-1 post-hoc analysis (n=2,542 women), published in Obesity journal 2025, found perimenopausal women on tirzepatide lost 23% of body weight vs 3% on placebo

Limit sugary drinks, as they don't hydrate as effectively and can impact blood sugar

However, many patients regain weight after stopping these medications and hence discussion needs to happen with your healthcare provider before stopping so that other interventions including diet and exercise are optimized

PMID: 1700785

When these bacteria ferment fiber, they produce short-chain fatty acids like butyrate, propionate, and acetate