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While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives

A new case report highlights the potential risk of "anhedonia" from high doses of tirzepatide, though it can be treated effectively.

Does GLP-1 affect liver enzymes

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Why weight-loss drugs may reduce heart attack and stroke risk
