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After we administered berberine stimulation, we found an increase in GLP-1 secretion by STC-1 cells, as well as an increase in the expression of molecules such as GLP-1R, PC1/3, PC2, and Pdx1

But this is the first clinical trial to find similar results

Beyond these regions, relevant GLP-1 receptor populations have been identified in at least 10 additional brain areas, pointing to physiological roles that extend well beyond feeding

J Am Pharm Assoc 2006

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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE