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GLP-1 receptor agonists commonly cause diarrhea due to delayed gastric emptying, increased intestinal transit time, altered gut microbiota composition, and p...

DPP-4 inhibitors were introduced for the treatment of type 2 diabetes in 2006

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Last week, Eli Lillys orforglipron has become the first oral, non-peptide GLP-1 receptor agonist to clear a Phase 3 trial, showing strong efficacy in reducing A1C (up to 1.6%) and body weight (up to 7.9%) in people with type 2 diabetes

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